A bioinformatic analysis in The Chinese Glioma Genome Atlas (CGGA) microarray and RNA sequencing databases [58] show that m6A writers, including METTL3, METTL14, WTAP, RBM15 and RBM15B, as well as m6A readers including YTHDC2, YTHDF1, YTHDF2, YTHDF3, hnRNPA2B1 and hnRNPC are elevated, while m6A writer ZC3H13 and m6A eraser FTO are decreased in gliomas. This evidence concerns the gene METTL3 and central nervous system cancer.