GSK3B and colonic neoplasm: Resveratrol is considered to be a promising anticancer drug for chemoprevention or therapy for colon cancer, targeting numerous cellular molecules, such as AKT serine/threonine kinase 1 (AKT1), AKT2 [19], and AKT/GSK-3β/Snail signaling pathway [20], and increasing ROS production [21].