MD simulations were also applied to explore states of CD1c in its apo-form and in two complexes with stearic acid and other small ligands [16] and to investigate how structural differences in mycolate lipids bound to CD1b impact the T-cell response in tuberculosis [17] However, the own process of lipid loading onto CD1 proteins is hard to address with all-atom MD calculations as it takes times well beyond the μs range [18]. The gene discussed is CD1C; the disease is tuberculosis.