SLC2A1 and cancer: Given the enhanced expression of GLUTs in some cancerous cells, it may seem curious that an extremely high contrast image of cancer by 2-FDG-PET is sometimes obtained, even though most cells, both cancerous and non-cancerous, take in 2-FDG through GLUT to a greater or lesser extent even when the imaging is conducted in a fasting condition to suppress uptake of the tracer in adipocytes and muscles [101].