BRCA2 and breast cancer: Section S3 (Supplementary Materials) provides information on dietary sources and estimated dietary intakes of acetaldehyde and formaldehyde, most notably alcoholic beverages for the former. A further study involved human cells collected from patients with a faulty copy of the BRCA2 breast cancer gene to investigate mechanisms associated with aldehyde-mediated cancer induction [146], and the investigators found that formaldehyde exposure leads to the degradation of cellular BRCA2 protein.