TP53 and cancer: Figure 8B presents the implication of miRNA in key biological processes. The miRnet network for common miRNA signatures emphasized an important number of target genes related to pathways in cancer (n = 118 targets, p-value = 1.7 × 10−97) cell cycle regulation (n = 54 targets, p-value = 4.76 × 10−43), apoptosis (n = 40 targets, p-value = 1.08 × 10−33) and TP53 signaling (n = 118 targets, p-value = 3.22 × 10−32) (Figure 8C).