SLC8A1 and diabetes mellitus: Table 1 shows varying degrees of depressions in SL Na+-K+-ATPase, SL Na+-Ca2+-exchanger, SR Ca2+-stimulated ATPase, SR Ca2+-uptake and MF Ca2+-stimulated ATPase was evident at 2 wks, whereas changes in cardiac function (LVEDP and LVSP), heart rate and mean arterial pressure were apparent at 4 wks after alloxan-induced diabetes [29,30].