PA2G4P4 and neoplasm: To study the PA2G4P4 RNA localization in BICa samples, in situ hybridization was performed using a digoxigenin-labelled PA2G4P4 RNA antisense probe (Figure 1) on both tumor samples, divided into low( LG) and high (HG) grade BlCa samples, and on adjacent bladder tissues (Figure 3).