Furthermore, several studies described elevated autoantibody concentrations in sera of patients with AIP including anti-lactoferrin [28,29], anti-carbonic anhydrase II, anti-carbonic anhydrase IV, anti-pancreas secretory trypsin inhibitor, anti-anionic and cationic trypsinogens, anti-amylase-1, anti-heat shock protein 10 and anti-plasminogen-binding protein peptide autoantibodies [7,18,30]. The gene discussed is CA4; the disease is autoimmune pancreatitis.