LTA and colorectal carcinoma: As shown in Figure 1A,B, we found that treatment of CRC cells (HCT116 and HCT116R) with Calebin A (2, 5 μM) by itself (p < 0.05) or as co-treatment with 5-FU (2 nM) and/or TNF-β (10 ng/mL) at Calebin A (5 μM) suppressed the proliferation capacity of HCT116 and HCT116R cells significantly by around 50% compared to untreated cells (Figure 1A,B).