The vital role of FOXF1 in the pathogenesis of IPF was later highlighted by the observation that loss of Foxf1 increased migration of pulmonary fibroblasts via facilitating CDH2-CDH11 cadherin switch and thus aggravated bleomycin-induced pulmonary fibrosis in mice [22]. This evidence concerns the gene CDH11 and idiopathic pulmonary fibrosis.