Malakar et al found that lncRNA metastasis‐associated lung adenocarcinoma transcript 1 (MALAT1) up‐regulated the expression of glycolytic genes and down‐regulated gluconeogenic enzymes by enhancing the translation of the metabolic transcription factor TCF7L2, which acts as a proto‐oncogene in HCC.45 This evidence concerns the gene TCF7L2 and hepatocellular carcinoma.