With point‐of‐care ultrasound examination, the presence of effusions or B‐lines in association with severe LA enlargement is highly suggestive of CHF.58, 115 A negative result on a point‐of‐care NT‐proBNP test suggests that respiratory disease is more likely to be the cause of respiratory distress than is cardiac disease. This evidence concerns the gene NPPB and congestive heart failure.