Despite the apparent limitations to establish the ascarid-urticaria association due to mite and shellfish sensitization or other helminth infections in our region, the results obtained in this work, where helminth poly-parasitism is very scarce, strongly suggest that specific IgE and IgG antibodies against Anisakis larva crude extract, Ani s 1 and tropomyosin could be considered markers for parasite-caused urticaria. Here, IGHE is linked to urticaria.