Whether the elevated CRP and PCT are associated with the severity of HFRS remains a controversial issue.[10–12] It is well accepted that the main clinical hallmarks of HFRS are renal failure and hemorrhagic manifestations and that the disease is characterized by laboratory findings indicating renal function impairment, thrombocytopenia, and elevated ALT levels.[9]. This evidence concerns the gene CALCA and Thrombocytopenia.