Kaplan–Meier analysis found that patients with high ApoB were significantly more likely to progress to RRT than those with low ApoB (log-rank = 16.62, p < 0.001; Figure 1), Cox regression analysis of the association between high ApoB versus low ApoB and progression of DKD to RRT is shown in Table 2. The gene discussed is APOB; the disease is diabetic kidney disease.