Our results are also in line with previous reports that G-CSF is localized at the invasive front of breast tumors and is highly expressed in TNBC, compared with ER-positive breast cancer tissues or normal tissues, with bad clinical outcomes (Park et al., 2011; Aliper et al., 2014; Swierczak et al., 2014; Benesch et al., 2015; Zhao et al., 2015; Mouchemore et al., 2018). This evidence concerns the gene CSF3 and breast carcinoma.