TNIK and infection: Purified splenic Cd45.1+Tnik−/− (KO) and Cd45.2+ TNIK competent (WT) p14 T cells were adoptively co-transferred (AdCoTf) at a ratio of 1:1 into Cd45.1+.2+-recipient mice 1 day prior to infection with 104 pfu LCMV (Fig. 3a).