BRCA1 and ovarian carcinoma: Stafford et al.19 conducted WES on 48 BRCA1 and BRCA2-negative ovarian carcinoma cases with a high prior likelihood of genetic susceptibility, but restricted their candidate gene variant analysis to 155 genes involved in DNA damage response or cell cycle regulation, along with 64 ovarian carcinoma-associated genes listed in the Human Gene Mutation Database (HGMD).