Exosome from sunitinib-resistant renal cancer cells could transfer lncARSR (lncRNA activated in RCC with sunitinib resistance) to sensitive cells, in which LncARSR competes with miR-34 and miR-449, promotes AXL and c-MET expression, reactivates RTKs, and mediates drug resistance42. Here, AXL is linked to renal carcinoma.