In contrast, higher expression of SEMA3B and SEMA3D was correlated with C5 over other infiltrate types, and SEMA3G had significantly higher expression in components C3 and C5 than in C1, C2, and C4, suggesting an association of higher gene expression with favorable immune composition, which indicates that these genes may mainly play a tumour suppressor role. The gene discussed is SEMA3G; the disease is neoplasm.