However, in the MONICA/KORA Augsburg study, the largest population-based study in European populations for IP-10 with CVD, the association of IP-10 with incident CHD was attenuated to insignificance (third tertile compared to first HR = 1.26 95% CI 0.94–1.69) after adjustment for established CHD risk factors.[19] Our results are essentially concordant with this estimate of small to no effect of IP-10 on CHD risk from the MONICA/KORA Augsburg study. This evidence concerns the gene CXCL10 and coronary artery disorder.