In populations of European origin, IP-10 was associated with incident coronary heart disease (CHD),[19] hypertension,[20] and symptomatic HF,[21] though these associations were not always robust to adjustment for CVD risk factors.[19] However, most studies to date were relatively small, and did not include AA populations who have a higher risk of CVD compared to non-Hispanic whites.[22]. This evidence concerns the gene CXCL10 and hydrops fetalis.