The results of blood NGAL in the hierarchical summary receiver operating characteristic model were β = -0.27 (95%CI:-1.14–0.59, Z = -0.62, P = 0.538), which reflected that the shape of the SROC curve was symmetric; and λ = 3.20, which indicated that the diagnostic accuracy of blood NGAL for CIN was moderate. The gene discussed is LCN2; the disease is cervical squamous intraepithelial neoplasia.