MASP1 and leprosy: Linkage disequilibrium between the intron 1 and exon 12 alleles resulted in a total of twelve different MASP1 haplotypes in leprosy patients and thirteen in controls, among which those with frequencies higher than 10% were GC_CCG, followed by GT_CCG, GC_CTG, GC_CCA and AC_CCG. Three of them were associated with leprosy, independently of any other demographic factor (Table 3).