Previous studies have suggested that LIMD1 participates in tumor progression of diverse cancers by serving as a tumor‐suppressor, such as in gastric cancer and cervical cancer.7, 8 Also, LIMD1 is revealed by former studies to present low expression and hinder tumor growth In NSCLC.9, 10 These findings indicated that the investigating LIMD1‐related mechanism in NSCLC progression might be helpful to provide new thoughts for molecular‐targeted treatments of NSCLC. This evidence concerns the gene LIMD1 and neoplasm.