CTNNB1 overexpression counteracted repressing effect of sh‐SNHG12#1 on migration, invasion, and EMT in ESCC cells, and such counteraction was furthered by co‐overexpression of CTNNB1 and BMI1 (Figs 7D,E and S8A). This evidence concerns the gene BMI1 and esophageal squamous cell carcinoma.