CTNNB1 overexpression counteracted repressing effect of sh‐SNHG12#1 on migration, invasion, and EMT in ESCC cells, and such counteraction was furthered by co‐overexpression of CTNNB1 and BMI1 (Figs 7D,E and S8A). Here, CTNNB1 is linked to esophageal squamous cell carcinoma.