The carcinogenesis function of SNHG family in cancers has been widely reported (Cai et al., 2017; Dong et al., 2018), and the participation of SNHG1 and SNHG7 in ESCC has been researched (Xu et al., 2018a; Zhang et al., 2017), so we focused on SNHG12 in our research. This evidence concerns the gene SNHG12 and cancer.