Reduced apoptosis is associated with the development of drug resistance (Chen et al., 2017; Li et al., 2014; Yochum et al., 2018), and in the current study, osimertinib induced apoptosis in EGFR‐mutant NSCLC cell lines but not in osimertinib‐resistant NSCLC cells. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.