It is also believed that immune reaction to the Hsp epitopes may be a link between infections and autoimmune diseases (Zugel and Kaufmann 1999), thus it could be implicated in the pathogenesis of such diseases as psoriasis, where response to the Hsps may be related to microbial foci complicating the course of this dermatosis (Besgen et al. 2010; Cancino-Diaz et al. 2004; Ishikara et al. 2000; Rambukkana et al. 1993). This evidence concerns the gene HSP90B2P and psoriasis.