In conclusion, high expression of ADRA2A (Figure 6A), CXCL12 (Figure 6B), S1PR1 (Figure 6C), ADAMTS9 (Figure 6D), F13A1 (Figure 6E), and SPON1 (Figure 6F) was associated with poor overall survival in bladder cancer patients, with a P-value <0.05 considered to be statistically significant. This evidence concerns the gene SPON1 and urinary bladder cancer.