VEGFA and periodontal disorder: These authors have indicated that the concentration of VEGF in gingival crevicular fluid was significantly correlated with both periodontal disease progression and healing after therapy.14 Miyagawa et al examined the localisation of VEGF in rat periodontal tissues during experimental tooth movement in vivo, and the effects of continuous compressive force on VEGF production and angiogenic activity in human periodontal ligament cells in vitro.