CRP and obesity due to melanocortin 4 receptor deficiency: Adjustment variables for multivariable-adjusted HRs included main covariates (age, sex, SBP, HbA1c, LDL-C, HOMA-IR, CRP, eGFR and use of antihypertensive medication) and obesity categorized by (a) BMI (≥27.5) or (b) waist circumference (WC ≥ 90 cm for men, ≥85 cm for women).