Since bacterial infections are a major cause of pregnancy complications and are able to induce and inflammatory process at the maternal/fetal interface including the expression of inflammatory cytokines/chemokines such as CXCL1058, we hypothesized that bacterial signals could induce CXCL10 expression by modifying the H3K27me3 mark and consequently promote the recruitment of maternal CD8+ T cells. This evidence concerns the gene CXCL10 and bacterial infectious disease.