Human cohort studies have shown that not only does CXCL10 expression increase with normal term labor (as do other inflammatory cytokines), but importantly, elevated levels of CXCL10 are associated with preterm birth and chorioamnionitis, suggesting that CXCL10 suppression in the decidua is necessary for the normal course of pregnancy21,87,89. Here, CXCL10 is linked to chorioamnionitis.