Moreover, our data further confirm that ZLMP2A-N110, by inhibiting phosphorylation of AKT, GSK-3β and β-catenin signalling proteins, can suppress nuclear translocation of β-catenin, which in turn decreases the expression of c-Myc oncogene and thereby reduces viability of NPC-derived cell lines. The gene discussed is AKT1; the disease is nasopharyngeal carcinoma.