Three significant loci were found from normal type gout: rs548944057 of SLC28A3-NTRK2 (pmeta=2.91×10–8; OR=4.04), rs4148155 of ABCG2 (pmeta=3.64×10–8; OR=2.34) and rs146978188 of CD2-PTGFRN (pmeta=4.93×10–8; OR=6.31). This evidence concerns the gene PTGFRN and gout.