Of these, PDZK1, a gene encoding a scaffolding protein22 23 such as for urate transporters SLC22A12/URAT1 and ABCG2, was reported to have an association with SUA by a GWAS approach24 25 and with gout as a result of candidate gene approach studies.26–28. Here, SLC22A12 is linked to Single umbilical artery.