CCL3 and myeloid sarcoma: Notably, genes related to T cell exhaustion (e.g. PDCD1, CTLA4 and 41-BB) were selectively upregulated in IR types, and genes related to macrophage and granulocyte infiltration and activation (e.g. TREM1, CSF3 and CCL3) were upregulated in the XB and MS types.