By gene enrichment analysis, we found that these genes were enriched in cytokine-cytokine receptor interaction, chemokine signaling pathways, leukocyte trans-endothelial migration, complement and coagulation cascades, antigen processing and presentation, intestinal immune network for IgA production, and inflammatory bowel disease (Supplementary Fig. 9a, b). The gene discussed is CD79A; the disease is inflammatory bowel disease.