Some of the proteins in these biological regulatory subclasses of interest were identified in both groups of patients as being more abundant in either non-relapsing HL (AGT, C1QB, EFEMP, TTR, FBLN1, HRG, PZP, SERPINA1, SERPINC1, SERPINF2 and PON1) or relapsing HL (A1BG, C1S, FGB, FGG, FN1 and THBS1). Here, HRG is linked to Hodgkins lymphoma.