CRP and rheumatoid arthritis: Several clinical studies have demonstrated that daily consumption of krill oil (2 g/day for 30 days) improves the subjective symptoms of knee pain in adults with mild knee pain [42], mitigates the subjective symptoms of OA as assessed by Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and reduces C-reactive protein (CRP) levels in patients with rheumatoid arthritis or OA with CRP levels greater than 1.0 mg/dL [43].