BCL2 and posterior cortical atrophy: The results from the GEO dataset [24,25] revealed that the mRNA expression of BCL2, a key player in the PCa cell apoptosis increased dramatically in both CRPC cell-derived tumors (LAPC9 androgen independent cells and LNCaP secondary CRPC cells) (Figure 1A) [24] and EnzR cell-derived tumors (CWR-R1, LAPC-4, LNCaP Enz-resistant cell) (Figure 1B) [25].