Another study checked the association between genetic variants of ALOX5, ALOX12, ALOX12B, and ALOX15, and type-2 diabetes mellitus (T2D), and found that ALOX12 and ALOX12B genetic variants increased susceptibility to T2D development, possibly though alterations in PUFA/ARA metabolism. Here, ALOX5 is linked to type 2 diabetes mellitus.