Pearson’s correlation test also showed that the expression of IMPA2 and the mTORC1 gene set in the TCGA ccRCC cohort, regardless of pathologic M status, appears to be negatively correlated (r = −0.382) with statistical significance (p = 7.92 × 10−19) (Figure 1D). This evidence concerns the gene IMPA2 and nonpapillary renal cell carcinoma.