Pemphigus and BP are identified by both circulating and tissue-bound autoantibodies against desmosomal cadherins (mainly desmoglein 1 and 3 (DSG1/3) in pemphigus) and dermal–epidermal junction components (mainly hemidesmosomal proteins, e.g., BP180 and BP230 in BP) [1,2,3]. Here, COL17A1 is linked to pemphigus.