Finally, we performed a targeted sequencing study that included mutated genes found in whole-genome/exome sequencing studies, genes frequently mutated in all cancers, and FOXA1 and the 0–200 kb upstream region in all 48 patients with EMPD and 14 patients with MPD (Figure 2, Tables S4 and S5). The gene discussed is FOXA1; the disease is extramammary Paget disease.