VIP and colorectal carcinoma: Among the 10 immune genes of prognostic value, used to build our model, Fatty Acid Binding Protein 4 (FABP4) [36, 37], NGF [38, 39], Resistin Like Beta (RETNLB) [40, 41], Urocortin (UCN) [42, 43], Vasoactive Intestinal Peptide (VIP) [44, 45], Nerve Growth Factor Receptor (NGFR) [46, 47] have been implicated in direct or indirect involvement in regulation of CRC development and metastasis through other pathways.