In bivariate analyses, those who had experienced a MI during follow-up were older, had longer diabetes duration, were more likely to be Indigenous Australians, current smokers, on insulin, have a history of severe hypoglycemia, angina, left ventricular hypertrophy, peripheral arterial disease, peripheral sensory neuropathy, higher systolic blood pressure, albuminuria, and worse kidney function (Additional file 1: Table SII). The gene discussed is INS; the disease is Hypoglycemia.