Furthermore, these data are consistent with genome-wide CRISPR-Cas9 dependency screens, with the CRISPR (Avana) Public 19Q4 screen identifying 240 of 689 cell lines from a wide range of different cancers as being LARP1 dependent (https://depmap.org/portal/gene/LARP1?tab=overview). The gene discussed is LARP1; the disease is cancer.