Another potassium channel gene identified with variants in our cohort was KCNAB1, which is strongly transcribed in the dorsolateral prefrontal cortex and encodes the potassium voltage channel Kv1.57 In this study, the case patient (R118) with a variant in KCNAB1 (p.Ala250Gly) suffered catastrophic cerebral edema following a trivial injury. This evidence concerns the gene KCNAB1 and edema.