Interestingly, circulating FGF21 levels in patients with AP were also strongly associated with the development of pathogenesis of AP (Figure 1A), and serum FGF21 levels in AP patients with critical condition were markedly higher than those in a stable condition (eg: 11 650 ± 3848 pg/mL vs 4421 ± 807 pg/mL at 7 days, P < .05). The gene discussed is FGF21; the disease is alkaline phosphatase measurement.