VWF and hemorrhage: All 3 VWD categories were associated with increased likelihood of hemorrhage compared with unknown VWD status (low VWF vs unknown: OR, 3.2 [95% CI, 1.9-5.5]; P < .001; normal VWF vs unknown: OR, 4.4 [95% CI, 3.5-5.6]; P < .001; and disease vs unknown: OR, 3.9 [95% CI, 0.8-18.3]; P < .001).