This daily analysis of protein kinetics revealed that IL-17C protein release predominantly occurred between 12 and 48 h and was no longer consistently released after 48 h, suggesting either that (1) early release of IL-17C persists without significant degradation up to 120 h post-infection, and/or (2) that the reduction in apically shed HRV due to daily washes also limits further infection of airway epithelial cells contributing to the reduction in IL-17C. Here, IL17C is linked to infection.